Asahi Kasei
World-leading hollow fiber membrane technology for superior tangential flow filtration performance
Company Overview
Asahi Kasei Corporation is a Japanese multinational chemical company founded in 1931, with a diverse portfolio spanning chemicals, materials, health care, and housing sectors. The company's Bioprocessing Division has emerged as a leader in hollow fiber membrane technology for biopharmaceutical applications.
Asahi Kasei's hollow fiber products are renowned for their exceptional performance in tangential flow filtration (TFF) applications, including concentration, diafiltration, and clarification of biopharmaceutical products. The company's proprietary membrane manufacturing processes ensure consistent quality and reliability.
With manufacturing facilities in Japan and the United States, Asahi Kasei serves biopharmaceutical companies worldwide, providing both standard products and custom solutions tailored to specific process requirements.
90+
Years History
#1
Hollow Fiber Technology
ISO
Certified Quality
Global
Supply Network
Core Product Lines
Hollow Fiber Microfiltration
Sterile filtration and clarification modules with precise pore sizes for cell removal, harvest, and sterile processing applications.
- •0.1μm to 1.0μm pores
- •Polyethersulfone (PES)
- •High flux rates
- •Low protein binding
Hollow Fiber Ultrafiltration
Concentration and diafiltration cartridges with various molecular weight cutoffs for protein purification and buffer exchange.
- •1kDa to 750kDa MWCO
- •Modified PES membranes
- •Wide pH stability
- •Excellent recovery
Spectrum™ Minichrome
Small-scale hollow fiber modules designed for process development, optimization, and small batch production runs.
- •Compact design
- •Low hold-up volume
- •Easy installation
- •Scalable geometry
Large Scale Modules
Industrial-scale hollow fiber cartridges for commercial manufacturing with high surface areas and robust construction.
- •Up to 5.5 m² surface
- •Multiple configurations
- •Steam sterilizable
- •Long service life
Custom Solutions
Tailored hollow fiber products designed to meet specific process requirements including unique potting materials and geometries.
- •Application-specific
- •Prototype development
- •Scale-up support
- •Technical partnership
TFF Systems & Accessories
Complete tangential flow filtration systems, pumps, holders, and accessories for laboratory and pilot-scale operations.
- •Ready-to-use systems
- •Compatible hardware
- •Process support
- •Training available
Technology Advantages
Superior Membrane Morphology
Unique asymmetric hollow fiber structure with optimized pore distribution delivering high flux while maintaining excellent retention characteristics.
Robust Chemical Compatibility
PES-based membranes withstand harsh cleaning and sanitization conditions including NaOH, enabling effective CIP and extended membrane lifetime.
Consistent Manufacturing Quality
Vertically integrated production from polymer synthesis to module assembly ensures tight quality control and lot-to-lot consistency.
Scalable Platform
Geometrically similar modules from lab to production scale enable straightforward process scale-up with predictable performance.
Key Application Areas
Protein Concentration & Diafiltration
Antibody concentration, buffer exchange, formulation adjustment, volume reduction
Cell Harvest & Clarification
Mammalian cell removal, fermentation broth clarification, debris separation
Virus Purification
Viral vector concentration, vaccine production, gene therapy vectors
Polysaccharide Processing
Vaccine antigen purification, carbohydrate concentration, desalting
Experience Asahi Kasei Performance
Discover the advantages of Asahi Kasei's hollow fiber technology for your bioprocessing applications with our expert support.
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